AI Cure is a research tool showing open data. Not medical advice. Discuss with your doctor. Terms

โ† Trials
๐Ÿงช

The Effects of Tyrosol and Creatine on Exercise Performance and Cognition in Healthy Adults

RecruitingNAAges 20 Years - 55 YearsMaleApplied Science & Performance Institute
๐Ÿ’ฌ

In plain words

What the trial is, and whether it could suit you

This study will be a randomized, double-blind, placebo-controlled trial. It will be conducted over a 8-week intervention investigating the effects of creatine (5g Creatine monohydrate); placebo control (5g resistant dextrin), and a combination group containing both creatine and tyrosol (5g creatine monohydrate + 150mg tyrosol/day). Endurance, strength, cognition, and fatigue resistance will be examined through repeated strength and endurance testing (described below). Participants who pass initial screening will be invited on-site for day one (Visit 1) of testing where the participants will proceed with a series of tests which will include the following: (1) body composition; (2) mood and cognitive testing; (3) full-body strength testing; (4) 5RM (repetition maximum) bench press, leading to multiple sets of bench press (based on the previous weight) completed to failure; (5) finally, a

Sign in to get the eligibility rules as simple questions to take to your doctor.

๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * Healthy males aged 20-55 * Currently active (engaged in moderate to vigorous activity at least 2-days per week as defined by the American College of Sports Medicine Guidelines) * Estimated VO2 max greater than the 40th percentile of the population norm for age (assessed via ACSM guidelines, 2014). The VO2 max estimation at screening will be obtained by following a non-exercise regression model validated and described by Bradshaw et al. (2005). * Able to read and write in English * During the study, agree not to take any other supplements that may increase muscle strength or endurance (e.g. protein formulas, creatine, amino acids, tyrosol or stimulants other than caffeine). * During the study, subjects will not deviate from their normal daily routine unless it conflicts with study criteria. This includes maintaining their present workout routine and diet, without substantial changes. Exclusion Criteria: * Known diagnosis of any cardiovascular, metabolic, endocrine, or renal disease * Uncontrolled stage II hypertension or higher * Recent musculoskeletal injury (\<3-months) * Recent orthopaedic surgery (\<12-months) * History of or current malignancy * Previous gastrointestinal surgery within the past 12 months * Regular smoker * Regular drinker (\>14 drinks per week) * Current use (within the past 5 weeks) of creatine supplements * Current use (within past 3 months) of Tyrosol supplementation * Current use of dietary supplements that may enhance mitochondrial function, muscle hypertrophy, or muscle strength (e.g. protein formulas, creatine, amino acids, tyrosol, etc.). * Current use of prescription medications that may influence adaptation to exercise (hormone therapies, peptides, etc.)
๐Ÿ’Š

What it tests

  • Tyrosol
  • Creatine Monohydrate
  • Resistant Dextrin
๐Ÿ“

Where

1 site
Applied Science and Performance Institute
Tampa, United States
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
๐Ÿ›ก๏ธ

AI Cure shows public evidence (Open Targets, ClinicalTrials.gov, PubMed, openFDA, DepMap, AlphaFold) with its source, and AI summaries that cite it โ€” not medical advice and not a cure. Treatment decisions belong with your doctor. Research ideas are shared only with approved researchers and labs, who can test them. In an emergency call your local emergency number (112 in India and Europe, 911 in the US). AI Cure Terms of Use ยท Privacy