🌐 EnglishEN

AI Cure is a research tool showing open data. Not medical advice. Discuss with your doctor. Terms

← Trials
🧪

The Many Roads to Trauma Recovery: A Clinical Trial Comparing Empirically Supported Treatments for Veterans With Co-Morbid Posttraumatic Stress and Substance Use Disorder Symptoms

RecruitingPhase 2, Phase 3Ages 18 Years - anyAllCoatesville VA Medical Center
NCT07756723 on ClinicalTrials.gov ↗
💬

In plain words

What the trial is, and whether it could suit you

Veterans with co-morbid posttraumatic stress disorder (PTSD) and substance use disorders (SUDs) are at substantial risk of developing hypertension and cardiovascular diseases that often lead to premature death, with some evidence that they may die over 10 years earlier than their counterparts. As such, determining ways to improve their health outcomes is vital. Heart Rate Variability Biofeedback (HRVB) may be one way to restore autonomic balance and teach veterans with PTSD / SUDs how to respond differently to their symptoms. Multiple studies have found that HRVB not only improves autonomic nervous system (ANS) regulation / flexibility among veterans with PTSD, but also reduces PTSD symptoms. Additionally, there is evidence that HRVB reduces cravings and SUD symptoms. Currently it is proposed that the improvement in the PTSD and SUD symptoms are due to a combination of improving ANS regu

Sign in to get the eligibility rules as simple questions to take to your doctor.

Sign in
📋 Eligibility rules (as published)
Inclusion Criteria: * PTSD diagnosis * Enrolled in VA healthcare * Attending residential programming at CVAMC * Current substance use difficulty based on screening questions Exclusion Criteria: * Non-English speaking * Inability to complete study procedures * Lack competency to provide consent * Acute intoxication of a substance * Active psychotic symptoms at the study visit * Suicidal or homicidal ideation with intent and planning * Pacemaker or other cardiovascular implants.
💊

What it tests

  • Trauma Informed Heart Rate Variability Biofeedback
  • Present Centered Therapy
📍

Where

1 site
Coatesville VA Medical Center
Coatesville, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
🛡️

AI Cure shows public evidence (Open Targets, ClinicalTrials.gov, PubMed, openFDA, DepMap, AlphaFold) with its source, and AI summaries that cite it — not medical advice and not a cure. Treatment decisions belong with your doctor. Research ideas are shared only with approved researchers and labs, who can test them. In an emergency call your local emergency number (112 in India and Europe, 911 in the US). AI Cure Terms of Use · Privacy