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Retrospective Validation of AccuPulmo CT Portal for Detecting Pulmonary Fibrosis on Chest CT

Recruitingn/aAges 20 Years - anyAllTaichung Veterans General Hospital
NCT07761377 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This retrospective observational study evaluates the diagnostic performance of AccuPulmo CT Portal, an artificial intelligence-assisted medical imaging software, for detecting pulmonary fibrosis on pre-existing chest computed tomography images. A total of 900 chest computed tomography examinations obtained at Taichung Veterans General Hospital between January 1, 2020, and December 31, 2024, will be retrospectively selected. The planned sample includes 300 examinations with pulmonary fibrosis and 600 examinations without pulmonary fibrosis. All study images will be de-identified and coded before evaluation. Three qualified specialists in pulmonology or radiology will independently review each image without access to the original radiology report or the artificial intelligence output. The reference standard will be established by majority agreement of at least two of the three specialist

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📋 Eligibility rules (as published)
Inclusion Criteria: * Participants aged 20 years or older at the time of the chest computed tomography examination * Participants who underwent chest computed tomography for pulmonary disease at Taichung Veterans General Hospital between January 1, 2020, and December 31, 2024 * Availability of a completed clinical radiology report * Availability of chest computed tomography images suitable for de-identification and analysis by AccuPulmo CT Portal * Availability of sufficient image information to permit blinded specialist assessment of pulmonary fibrosis Exclusion Criteria: * Missing or incomplete chest computed tomography images * Image quality insufficient for pulmonary fibrosis assessment * Cardiac implants or other devices that substantially interfere with lung texture assessment * Extensive pneumonia that substantially interferes with lung texture assessment * Pleural effusion that substantially interferes with lung texture assessment * Other image abnormalities or artifacts that preclude reliable evaluation of pulmonary fibrosis
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What it tests

  • AccuPulmo CT Portal
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Where

1 site
Taichung Veterans General Hospital City: Taichung
Taichung, Taiwan
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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