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A Post Authorization Registry Study of Participants Treated With LEQEMBI

Recruitingn/aAges any - anyAllEisai Limited
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In plain words

What the trial is, and whether it could suit you

To describe the incidence and severity of known adverse events, including amyloid-related imaging abnormalities-edema (ARIA-E), ARIA microhemorrhage and hemosiderin deposit (ARIA-H), and intracerebral hemorrhage greater than 1 cm in diameter in participants treated with LEQEMBI during routine clinical practice, summarizing the data overall and by apolipoprotein E4 variant (APOE4) genotype, concomitant antithrombotic therapy, and baseline magnetic resonance imaging (MRI) findings (comorbid cerebral amyloid angiopathy \[CAA\]). The secondary purpose of this study is, To describe progression to the next stage of Alzheimer's Disease (AD), stratified by ARIA and intracerebral hemorrhage greater than 1 cm. To describe previously unknown adverse events related to the long-term safety of LEQEMBI in routine clinical practice, which were not identified in clinical development, as assessed by se

Sign in to get the eligibility rules as simple questions to take to your doctor.

📋 Eligibility rules (as published)
Inclusion Criteria: * Participants with Alzheimer's Disease who are prescribed LEQEMBI in Canada. Exclusion Criteria: * None
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What it tests

  • No Intervention
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Where

17 sites
University of Calgary - Hotchkiss Brain Institute
Calgary, Canada
University of Alberta, Geriatric Division
Edmonton, Canada
University of British Columbia - CARD
Vancouver, Canada
UBC Victoria - Neil and Susan Manning Cognitive Health Initiative
Victoria, Canada
Kingston HHC (Queen University)
Kingston, Canada
Parkwood Hospital - London
London, Canada
Trillium Hospital
Mississauga, Canada
Bruyère Institute
Ottawa, Canada

…and 9 more on ClinicalTrials.gov.

🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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