🌐 EnglishEN

AI Cure is a research tool showing open data. Not medical advice. Discuss with your doctor. Terms

← Trials
🧪

Role of N-Acetylcysteine in Non-Acetaminophen-Induced Liver Failure

RecruitingNAAges 18 Years - 60 YearsAllKing Edward Medical University
NCT07765823 on ClinicalTrials.gov ↗
💬

In plain words

What the trial is, and whether it could suit you

This randomized controlled trial evaluates whether oral N-acetylcysteine (NAC), given alongside standard supportive care, improves survival and reduces mortality in patients with non-acetaminophen-induced acute liver failure (ALF), compared to supportive care alone. Secondary objectives are to assess NAC's effect on length of hospital stay and improvement in liver function tests. Sixty-two adult patients (18-60 years) will be randomized 1:1 to NAC or control, with outcomes assessed at 28 days (survival/mortality) and day 4 (liver function tests).

Sign in to get the eligibility rules as simple questions to take to your doctor.

Sign in
📋 Eligibility rules (as published)
Inclusion Criteria: * Male or female, aged 18-60 years * Diagnosed with non-acetaminophen- induced acute hepatic failure (per operational definition/EASL criteria) * Etiology other than acetaminophen overdose (viral hepatitis HAV/HBV/HEV, non-acetaminophen drug-induced liver injury, or idiopathic) * No NAC treatment received for current episode prior to enrollment Exclusion Criteria: * History of chronic liver disease or cirrhosis * Prior severe cardiac, renal, neurological, or infectious disease that could confound outcomes * Prior liver transplant or current transplant candidacy * Known allergy/contraindication to NAC * Pregnant women.
💊

What it tests

  • N Acetyl Cysteine
  • Standard supportive care
📍

Where

1 site
King Edward Medical University/Mayo Hospital Lahore
Lahore, Pakistan
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
🛡️

AI Cure shows public evidence (Open Targets, ClinicalTrials.gov, PubMed, openFDA, DepMap, AlphaFold) with its source, and AI summaries that cite it — not medical advice and not a cure. Treatment decisions belong with your doctor. Research ideas are shared only with approved researchers and labs, who can test them. In an emergency call your local emergency number (112 in India and Europe, 911 in the US). AI Cure Terms of Use · Privacy