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Studying NMDA and Sigma-1 in Smoking Cessation Treatment (SUMMIT)

RecruitingPhase 3Ages 18 Years - 65 YearsAllAxsome Therapeutics, Inc.
NCT07766655 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This study is a Phase 3, multicenter, randomized, double-blind, placebo- and active-controlled, parallel-group trial to evaluate the efficacy and safety of AXS-05 compared to placebo and bupropion for smoking cessation in adults.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Male or female, aged 18 to 65 (inclusive) Exclusion Criteria: * Unable to comply with study procedures. * Medically inappropriate for study participation in the opinion of the investigator.
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What it tests

  • AXS-05 (dextromethorphan-bupropion)
  • Bupropion
  • Placebo
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Where

26 sites
Clinical Research Site
Little Rock, United States
Clinical Research Site
Lemon Grove, United States
Clinical Research Site
Long Beach, United States
Clinical Research Site
Pomona, United States
Clinical Research Site
DeLand, United States
Clinical Research Site
Jacksonville, United States
Clinical Research Site
Orlando, United States
Clinical Research Site
Tampa, United States

…and 18 more on ClinicalTrials.gov.

🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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