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Long-term Safety of UAS-assisted vs Sheathless RIRS in Non-prestented Patients

Recruitingn/aAges 18 Years - anyAllAl-Azhar University
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In plain words

What the trial is, and whether it could suit you

This retrospective comparative cohort study will include adult patients who underwent primary RIRS for renal stones โ‰ค20 mm at Al-Azhar University Hospitals between January 2020 and December 2025. Patients will be classified by whether a ureteral access sheath (UAS) was used during the index RIRS, and all eligible patients will be invited for active long-term follow-up (minimum 12 months) to assess the composite outcome of delayed ipsilateral ureteral stricture or new/progressive ipsilateral hydronephrosis and other safety and efficacy outcomes. Propensity-score methods and adjusted regression analyses will be used to control confounding.

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๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * Age โ‰ฅ18 years at time of index RIRS. * Primary RIRS performed at Al-Azhar University Hospitals between Jan 1, 2020 and Dec 31, 2025. * Renal stone(s) with maximum diameter โ‰ค20 mm on preoperative imaging. * No ipsilateral ureteral stent or nephrostomy before index RIRS. * Documented operative record specifying whether a UAS was used. * At least 12 months elapsed since index RIRS. * Available contact information allowing invitation for active follow-up. Exclusion Criteria: * Primary ureteral stone treated during the same procedure. * Staghorn or \>20 mm stone burden. * Prior ipsilateral ureteral stricture or reconstructive surgery. * Congenital renal/ureteral anomalies affecting outcome (e.g., horseshoe kidney, duplicated system). * Incomplete operative or preoperative imaging records that preclude determination of eligibility or exposure (UAS use). * Additional ipsilateral ureteral procedure during follow-up that independently causes ureteral narrowing. * Refusal to participate in active follow-up or failure to attend after repeated attempts.
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What it tests

  • Ureteral access sheath-assisted RIRS
  • Sheathless RIRS
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Where

1 site
Department of Urology, Al-Hussein and Sayed Galal University Hospitals, Al-Azhar University
Cairo, Egypt
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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