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Cross-modal Neuromodulation to Improve Balance and Cognition in Older Adults With Glaucoma: A Randomized Trial of Cerebellar Transcranial Electrical Stimulation

RecruitingNAAges 55 Years - anyAllThe Hong Kong Polytechnic University
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In plain words

What the trial is, and whether it could suit you

The goal of this clinical trial is to use different tES techniques to constantly stimulate the cerebellum in older glaucoma patients. The main questions aim to answer : 1. If the different types of tES targeting the cerebellum can modulate glaucoma patients' balance function and visual-cognitive function? 2. Which tES techniques among the two types can benefit most? Participants will be required to receive the stimulation 15 times (3 sessions, 5 continuous days/session, 1-week interval between each session), and complete the balance and visual-cognitive function outcome measurements before and after each session.

Sign in to get the eligibility rules as simple questions to take to your doctor.

๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * Age over 55 years old; * Diagnosis of primary open-angle or normal-tension glaucoma with relative scotoma in both eyes; * Humphrey Field Analyzer visual field loss (mean deviation of โ‰ค- 6 dB) using the 24-2 testing protocol for both eyes; * Best-corrected distance visual acuity of 6/12 (equivalent to 0.3 logMAR) or better; * Cognitive functional score of 22 or above in the Montreal Cognitive Assessment -Hong Kong version (HK-MoCA). * Only the right-handed population will be recruited (screening by the Edinburgh Handedness Inventory). Exclusion Criteria: * Have musculoskeletal disorders or neurological diseases that can affect the balance or nervous system. * Ocular diseases other than glaucoma (e.g., age-related macular degeneration, diabetic retinopathy, moderate to severe cataract) or severe hearing impairment (to ensure that participants can hear the instructions clearly during assessments and training) * Have any contraindications for tES
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What it tests

  • transcranial electrial stimulation
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Where

1 site
Hong Kong Polytechnic University
Kowloon, Hong Kong
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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