AI Cure is a research tool showing open data. Not medical advice. Discuss with your doctor. Terms

โ† Trials
๐Ÿงช

Role of Pre-stenting Before Retrograde Intrarenal Surgery With Miniaturized Flexible Ureteroscopes

RecruitingNAAges 18 Years - 70 YearsAllAl-Azhar University
๐Ÿ’ฌ

In plain words

What the trial is, and whether it could suit you

This prospective randomized controlled trial will compare retrograde intrarenal surgery performed after routine preoperative ureteral stenting with direct retrograde intrarenal surgery without planned preoperative stenting in adults with unilateral renal calculi measuring 10-20 mm. The study will evaluate stone-free rate, ureteral access, need for rescue stenting, operative outcomes, complications, staged procedures, postoperative recovery, and auxiliary treatment.

Sign in to get the eligibility rules as simple questions to take to your doctor.

๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * Participants must meet all of the following criteria: * Adults aged 18-70 years. * Unilateral renal calculi. * Maximum total renal stone burden of 10-20 mm. * Planned treatment with RIRS. * Suitable candidate for elective endoscopic stone treatment. * Negative or appropriately treated preoperative urine culture. * Ability to provide written informed consent. * Ability and willingness to comply with postoperative follow-up, including non-contrast CT at 4 weeks after the final RIRS procedure. Exclusion Criteria: * Participants will be excluded for any of the following: * Bilateral renal calculi requiring simultaneous surgical treatment. * Active urinary tract infection, sepsis, or infected obstruction requiring urgent drainage. * Solitary kidney when randomization is considered clinically unsafe. * Known ureteral stricture or congenital ureteral abnormality likely to interfere with ureteroscopic access. * Previous failed ipsilateral ureteroscopic access requiring clinically indicated pre-stenting. * Existing ipsilateral ureteral stent or nephrostomy. * Previous ureteral reconstruction or urinary diversion. * Total renal stone burden greater than 20 mm. * Staghorn calculi. * Uncorrected coagulopathy. * Pregnancy. * Severe uncorrected cardiopulmonary disease precluding anesthesia. * Inability or unwillingness to provide informed consent. * Inability or unwillingness to comply with follow-up. * Any other condition judged by the treating surgeon to make randomization or RIRS clinically inappropriate or unsafe.
๐Ÿ’Š

What it tests

  • Preoperative double-J ureteral stenting followed by retrograde intrarenal surgery
  • Direct retrograde intrarenal surgery without planned preoperative ureteral stenting
๐Ÿ“

Where

1 site
Department of Urology, Al-Hussein and Sayed Galal University Hospitals, Al-Azhar University
Cairo, Egypt
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
๐Ÿ›ก๏ธ

AI Cure shows public evidence (Open Targets, ClinicalTrials.gov, PubMed, openFDA, DepMap, AlphaFold) with its source, and AI summaries that cite it โ€” not medical advice and not a cure. Treatment decisions belong with your doctor. Research ideas are shared only with approved researchers and labs, who can test them. In an emergency call your local emergency number (112 in India and Europe, 911 in the US). AI Cure Terms of Use ยท Privacy