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Effect of Early Versus Late Premolar Extraction on Orthodontic Tooth Movement

RecruitingNAAges 13 Years - 25 YearsAllShifa College of Dentistry
NCT07773389 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The goal of this randomized controlled trial is to evaluate whether the timing of premolar extraction affects the rate of orthodontic space closure during en-masse anterior retraction. The study will also assess gingival cleft formation, mesial movement of the upper first molars, ease and duration of premolar extraction, and patient-reported pain and anxiety. The main question it aims to answer is: Does early versus late premolar extraction affect the rate of orthodontic space closure? Researchers will compare two groups of patients. In the early extraction group the maxillary first premolars will be extracted before or within one week of start of fixed orthodontic treatment. In the late extraction group, the premolars will be extracted after alignment and immediately before the start of space closure. Participants will: * Receive fixed orthodontic treatment and bilateral extraction

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📋 Eligibility rules (as published)
Inclusion Criteria: 1. Age 13-25 years 2. No prior orthodontic treatment 3. Overjet 4-8 mm 4. Symmetric dental arches with mild to moderate crowding requiring bilateral first premolar extractions. 5. Probing depth less than 4 mm on all teeth Exclusion Criteria: 1. History of dental trauma 2. Poor oral hygiene 3. Syndromic patients 4. Systemic diseases or medications affecting bone metabolism
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What it tests

  • Early Maxillary First Premolar Extraction
  • Late Maxillary First Premolar Extraction
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Where

1 site
Shifa College Of Dentistry
Islamabad, Pakistan
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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