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Central Auditory Processing Modulation Underlying Anxiety Reduction Using Clinically Designed Improvisatory Music

RecruitingNAAges 55 Years - anyAllNorthwestern University
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In plain words

What the trial is, and whether it could suit you

This study examines whether Clinically Designed Improvisatory Music (CDIM) can reduce anxiety in people living with Alzheimer's disease and anxiety (AD-A), and whether it can also lessen caregiver burden. CDIM is a live, receptive music-based intervention that uses slow tempi, simple diatonic melodic lines, soft dynamics, and periodic pauses to promote relaxation. As described in the proposal, CDIM has previously been shown to reduce stress and improve physiological markers such as heart rate, blood pressure, and EEG alpha/beta ratios (CDIM significantly decreased physical stress symptoms and patients also reported positive emotional outcomes and EEG readings showed increased alpha/beta brainwave ratios ). The study will enroll 30 dyads (individuals with AD-A and their caregivers). Dyads will be randomly assigned to either CDIM or a control intervention (CI) consisting of calming short

Sign in to get the eligibility rules as simple questions to take to your doctor.

๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria * Clinical diagnosis of Alzheimer's Disease * Positive Alzheimer's disease biomarkers (blood test, amyloid PET scan or CSF) * Mini-mental State Exam (MMSE) \>=15 * Rating for Anxiety in Dementia (RAID) score \> 8 Exclusion Criteria * Significant hearing impairments * Major comorbidities Beck Depression Inventory (BDI) scores above \> 10'
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What it tests

  • Clinically Designed Improvisatory Music
  • Listening to Storytelling
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Where

1 site
Northwestern University Feinberg School of Medicine
Chicago, United States
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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