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Satiety, Microbiome, Appetite Regulation, and Tracking Energy Across Targeted Snacks: Acute Postprandial Study

RecruitingNAAges 35 Years - 65 YearsAllZoe Global Limited
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In plain words

What the trial is, and whether it could suit you

The goal of this clinical trial is to learn how eating different snack foods affects acute hunger, energy intake and eating behaviour in healthy adults. The study will be conducted remotely over 5 days. The main questions it aims to answer are: 1. Does eating a snack bar intervention change how hungry participants feel later in the same day? 2. Does eating a snack bar intervention change participants' energy intake, nutrient intake and eating behaviour on the same day? 3. Does eating a snack bar intervention change participants mood, energy levels and alertness later in the same day? Researchers will compare an intervention snack bar to a control snack bar to see if the intervention improves hunger, energy intake, eating behaviour, and other subjective measures. Participants will: * Eat 2 snack bars for breakfast on 2 separate days, with 2 days in between * Not eat anything after 9p

Sign in to get the eligibility rules as simple questions to take to your doctor.

๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * Willing and able to follow the study protocol * Willing and able to provide informed consent * Regular consumption of snacks (โ‰ฅ2 per day) * Fibre intake \<20 g/d * Living in the UK Exclusion Criteria: * Have BMI of less than 18.5 kg/mยฒ or more than 40 kg/mยฒ * Have an allergy or intolerance to ingredients in the intervention or control snack bars (including inulin) or cannot eat the food products safely and comfortably for any reason * Have a personal medical history of inflammatory bowel disease, coeliac disease, Crohn's disease, irritable bowel syndrome, chronic constipation, or chronic diarrhoea * Have started a new supplement in the past month, or are unwilling to maintain current supplement use throughout the study * Previously purchased any ZOE products (including Daily30, ZOE gut health bar or ZOE app membership). * Have taken any medication or product that may modify the measured study outcomes, in the past 3 months (including but not limited to: fibre supplements, antibiotics, non-topical steroids or other immunosuppressive medicines, probiotics or prebiotics, metformin, GLP-1 receptor agonists, lipid-lowering medications such as fibrates, statins, PCSK9 inhibitors, non-steroidal anti-inflammatory drugs) * Have used opiate pain medication or a proton pump inhibitor for 8 or more consecutive days during the past 3 months * Have experienced a heart attack, stroke or major surgery in the last 2 months * Have received treatment for cancer in the last 3 months * Are currently pregnant, breastfeeding or planning a pregnancy * Are diagnosed with an eating disorder, type 1 diabetes mellitus or type 2 diabetes mellitus
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What it tests

  • High-fibre plant-based snack bar
  • Control snack bars
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Where

1 site
ZOE limited
London, United Kingdom
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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