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How the Brain and Body Recover After a Wrist Fracture

Recruitingn/aAges 18 Years - anyAllCambridge University Hospitals NHS Foundation Tru…
NCT07777081 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

What is the problem? A wrist fracture is a common injury, affecting about 100,000 people in the UK each year. While most people recover well, a significant minority, between 10% and 20%, develop persistent pain and disability that lasts long after the bone has healed. In some cases this leads to a severe chronic pain condition called Complex Regional Pain Syndrome (CRPS). Currently we cannot easily predict who will recover and who may not, making it challenging to provide early targeted support. What are we trying to find out? We want to see if we can identify "signs" in the body, such as genetic markers, chemical messengers in the blood, and heart rate rhythms, that predict a person's recovery. We are also investigating the brain's "internal map" of the body. After an injury, this map can sometimes become "blurred" or less precise, which we believe is linked to ongoing pain. Our goal i

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📋 Eligibility rules (as published)
Inclusion Criteria: Distal radius fracture (DRF) within past 6 weeks 18 and older Willing and competent to complete the informed consent process Exclusion Criteria: Inability to understand the informed consent process (Language, competence) Multiple trauma Significant neurological disease (multiple sclerosis, previous traumatic brain injury, previous stroke or cerebral haemorrhage and substantial tremor - including Parkinson's, significant resting tremor, or other aetiology) Amputation or medical confirmation of unilateral sensory deficit
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What it tests

  • Not listed
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Where

1 site
Addenbrooke's Hospital
Cambridge, United Kingdom
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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