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A Study to Learn About the Study Medicine Called Tilrekimig in People With Moderate-to Severe Eczema

RecruitingPhase 3Ages 12 Years - anyAllPfizer
NCT07783425 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The purpose of this study is to find out how well tilrekimig works, how safe it is, and how it affects the body in adults and adolescents with moderate to severe atopic dermatitis (eczema). Eczema is a condition which can cause dryness, itching, and redness of your skin. The study is seeking participants who: * Are aged 12 years or older. * Were confirmed to have atopic dermatitis (AD) at least 12 months ago. * Are not having an effective treatment result from medicines that are applied on skin for AD. * Are considered by their doctors to have moderate to severe AD. The study treatment period will be 52 weeks. During the 24-week initial treatment period, participants will be randomized to one of three study treatments - tilrekimig, dupilumab, or placebo. Placebo does not have any medicine in it but looks just like the medicine being studied. These treatments will be randomized based o

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📋 Eligibility rules (as published)
Key Inclusion Criteria * You are \[12\] years of age or older * You have had moderate-to-severe eczema for at least 1 year * Topical medicines for eczema have not worked well for you Key Exclusion Criteria * Clinically Significant Autoimmune Disease * Significant Infection History or Active Infection * Known or Suspected Immunodeficiency/Immunosuppression * Significant psychiatric illness or suicidality * Clinically significant hepatic, renal, or hematologic abnormalities
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What it tests

  • Tilrekimig
  • Dupilumab
  • Placebo for Tilrekimig
  • Placebo for Dupilumab
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Where

32 sites
Alliance Dermatology & MOHS Center
Phoenix, United States
Dermatology Trial Associates, Inc.
Bryant, United States
Marvel Clinical Research
Huntington Beach, United States
California Allergy & Asthma Medical Group
Los Angeles, United States
Northridge Clinical Trials, LLC
Northridge, United States
Clinical Neuroscience Solutions, LLC
Orlando, United States
Marietta Dermatology Clinical Research, Inc.
Marietta, United States
Treasure Valley Medical Research
Boise, United States

…and 24 more on ClinicalTrials.gov.

🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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