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โ† Trials
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Sensory and Physical Reactions to Beverage Cues

RecruitingNAAges 21 Years - 70 YearsAllUniversity of Texas Southwestern Medical Center
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In plain words

What the trial is, and whether it could suit you

The goal of this clinical trial is to evaluate changes in craving and sensory responses to different beverage cues in adults (aged 21-70) with current mild or greater alcohol use disorder (AUD). The main questions it aims to answer are: * Does exposure to different beverage cues elicit distinct changes in subjective craving? * How do beverage liking, peak craving, and the return of craving to baseline compare across different test-beverage conditions? Researchers will compare Session A (Test Beverage Condition A) to Session B (Test Beverage Condition B) in a randomized crossover design to see if sensory and expectancy effects influence craving responses without consumption. Participants will: * Complete two separate 3-minute cue reactivity trials per session (a baseline water cue, followed by a test-beverage cue) while listening to guided audio instructions and holding/smelling the b

Sign in to get the eligibility rules as simple questions to take to your doctor.

๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * Age 21-70 years. * Current AUD (mild or greater severity on the SCID-5). * Regular drinkers (at least one drink in past week as identified in TLFB) able to identify a preferred alcoholic beverage (e.g., beer, wine, spirits, or mixed) for which a visually matched non-alcoholic alternative exists and can be sourced . * Willing to abstain from alcohol for โ‰ฅ12 hours prior to each session and arrive with BrAC = 0.000% at visit 1 and โ‰ค 0.020% at visit 2. BrAC will be collected immediately after the participant signs the consent form at visit 1. Exclusion Criteria: * CIWA-Ar โ‰ฅ10 which suggests clinically meaningful withdrawal. * Pregnancy, nursing, or planning pregnancy. * Medical contraindications to any alcohol exposure (e.g., liver disease, unstable cardiovascular condition). * Current use of medications that strongly affect craving or alcohol consumption (e.g., naltrexone, acamprosate, disulfiram). * Severe psychiatric illness or symptoms (e.g., bipolar disorder, schizophrenia, active suicidal ideation) that would interfere with procedures.
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What it tests

  • Alcohol Cue Reactivity Paradigm
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Where

1 site
Univeristy of Texas Southwestern Medical Center
Dallas, United States
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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