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Comparison Low-volume Versus Standard-volume Ultrasound-guided Bilateral Intermediate Cervical Plexus Block

RecruitingPhase 4Ages 18 Years - 65 YearsAllAssiut University
NCT07789548 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Thyroidectomy is commonly associated with mild-to-moderate postoperative pain that may affect respiratory function and recovery. Bilateral intermediate cervical plexus block provides effective analgesia, but larger local anesthetic volumes may increase phrenic nerve spread and diaphragmatic dysfunction. Low-volume ultrasound-guided block may provide adequate analgesia while better preserving diaphragmatic function and postoperative respiratory performance

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📋 Eligibility rules (as published)
Inclusion Criteria: * Adult patients aged between 18 and 65 years. * Patients scheduled for elective thyroidectomy under general anesthesia. * American Society of Anesthesiologists (ASA) physical status I-II. * Both sexes will be included. * Patients able to understand the study protocol and provide written informed consent. Exclusion Criteria: * Patient refusal. * Other endocrine diseases (as uncontrolled diabetes mellitus, adrenal disorders, pituitary disorders) * Known allergy or hypersensitivity to local anesthetics. * Coagulopathy or ongoing anticoagulant therapy contraindicating regional anesthesia. * Local infection at the site of needle insertion. * Preexisting diaphragmatic dysfunction or phrenic nerve palsy. * Significant chronic respiratory disease affecting pulmonary function (e.g., severe COPD, restrictive lung disease, uncontrolled asthma). * Morbid obesity (BMI ≥ 35 kg/m²). * Psychiatric or neurological diseases affecting respiratory muscles. * Previous neck surgery or anatomical deformity interfering with cervical plexus --block performance or diaphragmatic ultrasound assessment. * Pregnancy..
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What it tests

  • Bupivacain only
  • Bupivacain only
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Where

1 site
Assiut main university hospital
Asyut, Egypt
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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