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Patient-Reported Outcomes for Different Orthodontic Thermoplastics Used in Clear Aligners

RecruitingNAAges 15 Years - 30 YearsAllCMH Lahore Medical College and Institute of Denti…
NCT07790315 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Clear aligner therapy is an esthetic orthodontic treatment modality that uses removable thermoplastic trays to correct dental alignment. Different thermoplastic materials, including thermoplastic polyurethane (TPU) and polyethylene terephthalate glycol (PETG), may differ in flexibility and mechanical behavior. These material differences may influence patient-reported outcomes such as pain, mucosal ulceration, tooth sensitivity, tooth mobility, and material-related allergic symptoms. This randomized, double-blind, parallel-group clinical trial will compare patient-reported outcomes in patients treated with clear aligners fabricated from TPU versus PETG. Participants requiring non-extraction clear aligner therapy for mild to moderate crowding will be randomly allocated in a 1:1 ratio to receive aligners fabricated from either PETG or TPU. Outcomes will be recorded at five predefined time p

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📋 Eligibility rules (as published)
Inclusion Criteria: * • Patient aged between 15 and 30 years. * Permanent dentition, with all permanent teeth from first molar to first molar present. * Mild to moderate crowding less than 8 mm. * Non-extraction orthodontic treatment plan. * Ability and willingness to wear aligners for the required time. * Willingness to attend regular visits during orthodontic treatment. Exclusion Criteria: * • Syndromic patients. * Known allergy to thermoplastic materials. * Patients with systemic diseases that may affect orthodontic treatment or outcome assessment. * Patients requiring extraction as part of orthodontic treatment.
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What it tests

  • Device / orthodontic clear aligner material
  • Device / orthodontic clear aligner material
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Where

1 site
CMH Lahore Medical college and institue of dentistry
Lahore, Pakistan
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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