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Effects of VX-407 on the Pharmacokinetics of Combined Oral Contraceptives

RecruitingPhase 1Ages 18 Years - 50 YearsFemaleVertex Pharmaceuticals Incorporated
NCT07792408 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The purpose of the study is to evaluate the pharmacokinetic effects and safety and tolerability of VX-407 when coadministered with oral contraceptives.

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📋 Eligibility rules (as published)
Key Inclusion Criteria: * Body mass index (BMI) of 18.0 to 30.0 kilogram per meter square (kg/m\^2), inclusive * A total body weight of greater than (\>) 50 kg Key Exclusion Criteria: * History of febrile illness within 5 days before the first dose of study drug * Pregnant, nursing, or planning to become pregnant during the study or within 90 days after the last dose of study drug Other protocol defined Inclusion/Exclusion criteria will apply.
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What it tests

  • VX-407
  • LNG/EE
  • NGM/EE
  • NET/EE
  • DRSP/EE
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Where

1 site
Altasciences - Beaumont Clinic Montreal
Montreal, Canada
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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