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Sleep Apnea Biomarkers and Adherence to Continuous Positive Airway Pressure

Recruitingn/aAges 18 Years - anyAllClinique du Millenaire
NCT07792746 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Obstructive sleep apnea (OSA) is commonly assessed using the apnea-hypopnea index, although this measure does not fully reflect cardiovascular risk or the physiological impact of the disease. Emerging biomarkers, including sleep apnea-specific hypoxic burden, pulse wave amplitude drop index, and heart rate response, may provide additional information on cardiovascular vulnerability. This prospective multicenter observational study will investigate the association between these biomarkers, measured from the diagnostic sleep study, and adherence to continuous positive airway pressure (CPAP) therapy after three months. Symptoms, quality of life, clinical characteristics, and changes in biomarkers under continuous positive airway pressure will also be evaluated.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Newly diagnosed obstructive sleep apnea with an indication for continuous positive airway pressure therapy * Age older than 18 years * Written informed consent obtained Exclusion Criteria: * Continuous positive airway pressure treatment during the preceding 3 months * Medical contraindication to continuous positive airway pressure therapy * Concomitant condition likely to affect adherence to continuous positive airway pressure, including severe cognitive impairment or an unstable psychiatric disorder
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What it tests

  • Continuous Positive Airway Pressure
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Where

1 site
Clinique Millenaire
Montpellier, France
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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