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Early Warning and Stratified Diagnosis of Postoperative Respiratory Failure Based on Ventilator Waveform Image Features

Recruitingn/aAges any - anyAllWest China Hospital
NCT07799636 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

I. Study Background Postoperative respiratory failure (PRF) is a common and serious complication following major surgery, significantly increasing the rates of ICU admission and mortality. Traditional early warning methods primarily rely on blood gas analysis and vital sign monitoring, which are often delayed and may fail to identify early pathological changes in a timely manner. In recent years, ventilator waveforms, as dynamic information that directly reflects respiratory mechanics and airway conditions, have gradually attracted increasing attention in the optimization of respiratory support. International studies have suggested that analysis of ventilator waveform features may help identify patient-ventilator asynchrony, excessive spontaneous respiratory effort, ventilation-perfusion mismatch, and ventilator-related complications. In China, although a limited number of studies have e

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📋 Eligibility rules (as published)
Inclusion Criteria: * Age ≥18 years; * Patients receiving mechanical ventilation after surgery and transferred directly to the ICU; * Patients expected to require or actually requiring mechanical ventilation for more than 24 hours after surgery; * Patients or their legally authorized representatives providing written informed consent. Exclusion Criteria: * Respiratory failure occurring before surgery; * Severe pulmonary disease diagnosed before surgery, including but not limited to severe chronic obstructive pulmonary disease (COPD; GOLD stage 3-4), severe interstitial lung disease (PaO₂/FiO₂ \<300 mmHg), active pneumonia, and severe pulmonary hypertension; * Preoperative mechanical ventilation for \>48 hours; * A decision made immediately after surgery to withhold or withdraw active treatment, including invasive mechanical ventilation; * Expected survival of less than 48 hours; * Inability to connect to or record the required ventilator waveform data and/or electronic medical record data; * Other severe underlying diseases, including but not limited to end-stage liver disease, dialysis-dependent renal failure, and advanced malignancy with a short expected survival.
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What it tests

  • Not listed
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Where

1 site
Chi Zhang
Chengdu, China
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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