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Efficacy and Mechanism of Transcranial Temporal Interference Stimulation (tTIS) for Patients With Obsessive-Compulsive Disorders

RecruitingNAAges 18 Years - 65 YearsAllBeijing HuiLongGuan Hospital
NCT07805200 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Targeted temporal interference stimulation (tTIS) of the nucleus accumbens (NAc) may modulate the abnormal electrophysiological activity in individuals with obsessive-compulsive disorder (OCD), thereby improving their obsessive-compulsive symptoms.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Were between 18 and 65 years old; * Were diagnosed with OCD by an experienced psychiatrist utilizing the Structured Clinical Interview for DSM-5 (SCID); * Were able to participate in the entire trial and face-to-face on-site assessment Exclusion Criteria: * Pregnant or breastfeeding; * Suffered from organic brain diseases or severe physical illness; * Had a history of substance or alcohol abuse; * Presence of comorbid psychiatric disorders (e.g., major depressive disorder) or a high risk of suicide; * Have received electroconvulsive therapy, transcranial magnetic stimulation, tDCS, tACS, or other neurostimulation treatments within the past 6 months; * Presence of contraindications to MRI or tTIS, such as severe head trauma, prior brain surgery, intracranial or cardiac metallic implants, etc.
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What it tests

  • Transcranial Temporal Interference Stimulation
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Where

1 site
The Fourth People's Hospital of Anhui Province
Hefei, China
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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