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Incremental Dead Space Versus Capping Trial Before Tracheostomy Decannulation

RecruitingNAAges 18 Years - anyAllPontificia Universidad Catolica de Chile
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In plain words

What the trial is, and whether it could suit you

Some critically ill patients need a breathing tube placed directly into the windpipe (tracheostomy) because they require long-term help from a breathing machine. Before this tube can be safely removed (decannulation), medical team need to confirm the patient is ready to breathe on their own through the nose and mouth again. The most common way to check this is a "capping trial," in which the tube is blocked so air must pass through the upper airway, similar to normal breathing. However, because the tube itself remains in place during this test, it narrows the airway and may make breathing harder than it would be if the tube were actually removed. This could cause some patients to fail the test even though they are truly ready for the tube to come out, leading to unnecessary delays. This study will compare the standard capping trial with a new approach that instead adds extra tubing (dea

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📋 Eligibility rules (as published)
Inclusion Criteria: * Adult patients (≥18 years) admitted to the ICU. * Presence of a tracheostomy due to prolonged mechanical ventilation (≥14 days). * Clinically considered ready for decannulation, according to institutional criteria (e.g., stable gas exchange, minimal secretions, effective cough, and tolerance to spontaneous breathing). * Ability to maintain spontaneous breathing without mechanical ventilation for more than 48 consecutive hours. * Able to cooperate and follow basic commands (RASS between -1 and +1). * Written informed consent obtained from patient. Exclusion Criteria: * Neuromuscular disease affecting respiratory muscles (e.g., myasthenia gravis, Guillain-Barre syndrome, amyotrophic lateral sclerosis). * Hemodynamic instability. * Severe agitation or delirium precluding cooperation (RASS \< -2 or \> +2). * Structural airway abnormalities (e.g., subglottic stenosis, tracheomalacia). * Pregnancy. * Contraindications for esophageal balloon catheter insertion (e.g., severe coagulopathy, esophageal varices, and history of esophageal or gastric surgery). * Refusal to participate by the attending physician.
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What it tests

  • Incremental Instrumental Dead Space
  • Capping Trial
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Where

1 site
Hospital Clínico UC CHRISTUS, Unidad de Paciente Crítico
Santiago, Chile
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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