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Study on the Ultrasound and Biological Characteristics of Atypical Endometriosis.

Recruitingn/aAges 18 Years - anyFemaleCasa di Cura Dott. Pederzoli
NCT07816133 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This study hypothesizes that the histological, immunophenotypic, and molecular characterization of atypical endometriotic lesions may be related to specific clinical and ultrasound features.Identifying potentially atypical lesions would allow for more accurate stratification of patients, distinguishing definitely benign from potentially atypical endometriosis. The targeted study of endometriosis, both typical and atypical, also with reference to the inflammatory microenvironment, as well as immunophenotypic and molecular characteristics, could allow the formulation of pathogenic hypotheses on the development and progression of atypia towards malignant neoplasms.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Age \> 18 years * Candidate patients for endometriosis surgery with deep endometriosis (intestine, LUS) and/or endometrioma localizations. * Patients who are candidates for surgery for established or suspected endometrial and/or ovarian neoplasm * Patients who have performed a level II gynecological ultrasound with an experienced operator in the preoperative process. * Patients where there is the technical possibility of performing a transvaginal and/or transrectal ultrasound and the patient's willingness to undergo such an investigation. * Signing of informed consent. Exclusion Criteria: * Technical impossibility of performing a transvaginal ultrasound (patient virgo, patient refusal). * Previous neoplasms * Patient who does not provide their informed consent.
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What it tests

  • Retrospective case-control analysis
  • prospective case-control group
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Where

1 site
Ospedale P. Pederzoli Casa di Cura Privata S.p.A.
Peschiera del Garda, Italy
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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