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Peroxide Versus Non-Peroxide In-Office Tooth Bleaching

RecruitingNAAges 18 Years - 45 YearsAllMinia University
NCT07818031 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This randomized clinical trial aims to compare the effectiveness of peroxide and non-peroxide in-office tooth bleaching systems. The study will evaluate tooth whitening efficacy, color durability over time, and tooth sensitivity after treatment. Participants will receive one of the two bleaching treatments and will be followed for six months to assess the clinical outcomes and compare the performance of both systems.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Adults aged 18-45 years. * Good general health. * Presence of all maxillary anterior teeth free from restorations, caries, or structural defects. * Baseline tooth shade suitable for bleaching assessment. * Good oral hygiene and periodontal health. * Willingness to comply with the study protocol and attend all follow-up visits. * Signed informed consent. Exclusion Criteria: * Pregnancy or lactation. * History of tooth hypersensitivity. * Active caries or defective restorations in the anterior teeth. * Intrinsic tooth discoloration (e.g., fluorosis, tetracycline staining). * Ongoing orthodontic treatment. * Smoking. * Use of tooth-whitening products within the previous 6 months. * Allergy to any component of the bleaching materials.
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What it tests

  • peroxide -based in office tooth bleaching
  • non-peroxide -based in office tooth bleaching
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Where

1 site
Minia University Hospital
Minya, Egypt
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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