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Antibacterial Effects of Intracanal Medicaments in Acute Apical Abscesses

RecruitingNAAges 18 Years - 65 YearsAllAtaturk University
NCT07819240 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This randomized clinical trial compares the antibacterial effects of calcium hydroxide and a calcium silicate-based intracanal medicament in teeth with acute apical abscesses. Microbiological samples are collected before root canal preparation, after chemomechanical preparation, and after intracanal medication. Bacterial levels are measured using Real-Time PCR. The main objective is to determine which intracanal medicament provides a greater reduction in the total bacterial load after a 7- to 10-day medication period.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Diagnosis of acute apical abscess * A single-rooted permanent tooth requiring primary endodontic treatment * Age between 18 and 65 years * No history of systemic disease * American Society of Anesthesiologists physical status classification I (ASA I) * Provision of written informed consent Exclusion Criteria: * Previous endodontic treatment of the affected tooth * Periodontal probing depth greater than 4 mm * History of trauma involving the affected tooth * Pregnancy or breastfeeding * Immunodeficiency
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What it tests

  • Calcium Hydroxide Intracanal Medicament
  • Calcium Silicate-Based Intracanal Medicament
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Where

1 site
Ataturk University Faculty of Dentistry
Erzurum, Turkey (Türkiye)
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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