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NMR Metabolomics-Based Risk Assessment and Stratified Digital Health Interventions in Middle-Aged Adults (PREMAP)

RecruitingNAAges 45 Years - 55 YearsAllUniversity of Eastern Finland
NCT07820800 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

PREMAP invites residents of the Eloisa region (South Savo, Finland) turning 45, 50, or 55 years of age in 2026 to undergo a blood-based NMR metabolomics risk assessment for five interlinked cardio-renal-metabolic conditions (type 2 diabetes, coronary heart disease/myocardial infarction, stroke/cardiovascular disease, chronic kidney disease, and fatty liver disease), alongside a mental wellbeing assessment (WHO-5 Well-Being Index). Based on this risk profile, participants are classified as low, moderate, or high multi-disease risk. Participants at moderate or high risk are individually randomized in a 1:1:1 ratio to one of three digital health interventions for up to 12 months: a habit-based lifestyle application (BitHabit), a structured digital lifestyle coaching programme (Onnikka), or a guideline-based digital self-care pathway (Oma Eloisa, comparator). Participants at high risk additi

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📋 Eligibility rules (as published)
Inclusion Criteria: * Permanent resident of the Eloisa Wellbeing Services County (South Savo, Finland), or has selected Eloisa primary health care as their primary public care provider * Turning 45, 50, or 55 years of age during calendar year 2026 * NMR metabolomics-based risk assessment result classified as low, moderate, or high multi-disease risk * Able to provide written informed consent digitally * Able to use a smartphone, tablet, or computer for digital application access * Resident of Finland with a Finnish personal identity code (required for health register linkage) Exclusion Criteria: * Currently pregnant or breastfeeding * Incarcerated or under forensic psychiatric care * Significantly impaired capacity for self-determination * Insufficient proficiency in Finnish to provide informed consent and complete study procedures * No Finnish personal identity code
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What it tests

  • Digital health interventions
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Where

1 site
Wellbeing Services County of South Savo (Eloisa) (provide social and healthcare services and emergency services in the Enonkoski, Hirvensalmi, Juva, Kangasniemi, Mikkeli, Mäntyharju, Pieksämäki, Puumala, Rantasalmi, Savonlinna ja Sulkava)
Savonlinna, Finland
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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