AI Cure is a research tool showing open data. Not medical advice. Discuss with your doctor. Terms

โ† Trials
๐Ÿงช

Does Paracetamol Influence the Release of Gut Hormones, Glucose Absorption and Glycemia?

RecruitingNAAges 18 Years - anyAllUniversity of Copenhagen
๐Ÿ’ฌ

In plain words

What the trial is, and whether it could suit you

The study aim is to determine whether acute inhibition of endogenous prostaglandin synthesis by paracetamol affects the release of gut hormones, glucose absorption and glycemia in healthy young individuals

Sign in to get the eligibility rules as simple questions to take to your doctor.

๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * Age โ‰ฅ 18 years * Nondiabetic fasting plasma glucose (\< 7.0 mmol/L) at time of inclusion * BMI of 20-25 * Written informed consent Exclusion Criteria: * Haemoglobin \< 7.9 mmol/L * Pregnancy or breastfeeding * Significant gastrointestinal symptoms (e.g. dyspepsia, postprandial pain) * Use of medication that cannot be paused for 12 hours or any drug that affects gastric emptying, small intestinal motility, glucose absorption. * Use of paracetamol, NSAID, aspirin or similar within the previous week. * Evidence of drug abuse, consumption of tobacco in any form or daily consumption of more than 20g alcohol * History of gastrointestinal disease, including significant upper or lower gastrointestinal symptoms, pancreatitis, or previous gastrointestinal surgery including cholecystectomy (but not uncomplicated appendicectomy) * Participation in other research studies within the previous 3 months * Inability to give informed consent * Intolerance to any of the components of paracetamol and the meals used for the study
๐Ÿ’Š

What it tests

  • Paracetamol
  • Placebo
๐Ÿ“

Where

2 sites
Department of Biomedical Sciences, The Panum Institute, University of Copenhagen,
Copenhagen, Denmark
Hvidovre Hospital, Copenhagen University Hospital
Hvidovre, Denmark
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
๐Ÿ›ก๏ธ

AI Cure shows public evidence (Open Targets, ClinicalTrials.gov, PubMed, openFDA, DepMap, AlphaFold) with its source, and AI summaries that cite it โ€” not medical advice and not a cure. Treatment decisions belong with your doctor. Research ideas are shared only with approved researchers and labs, who can test them. In an emergency call your local emergency number (112 in India and Europe, 911 in the US). AI Cure Terms of Use ยท Privacy