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Preoperative Oral Carbohydrate Loading and Gastrointestinal Recovery After Bariatric Surgery in Metabolic Syndrome

RecruitingNAAges 18 Years - 65 YearsAllFirst Affiliated Hospital of Chongqing Medical Un…
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In plain words

What the trial is, and whether it could suit you

This prospective randomized controlled trial aims to evaluate the effect of preoperative oral carbohydrate loading on postoperative gastrointestinal recovery in patients with metabolic syndrome undergoing bariatric surgery. Eligible participants will be randomly assigned to either a preoperative oral carbohydrate drink group or a standard preoperative fasting group. The primary objective of this study is to determine whether preoperative oral carbohydrate loading can facilitate early postoperative gastrointestinal recovery. Outcome measures will include the proportion of patients achieving postoperative gastrointestinal recovery, time to postoperative gastrointestinal recovery, perioperative blood glucose levels, and other postoperative recovery-related outcomes. This study aims to provide clinical evidence regarding the efficacy and safety of preoperative oral carbohydrate loading in p

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📋 Eligibility rules (as published)
Inclusion Criteria: 1. adults aged 18-65 years; 2. diagnosis of metabolic syndrome (≥3 of the following: elevated waist circumference, elevated triglycerides, elevated blood pressure, elevated fasting glucose, and reduced HDL-C); 3. eligibility for bariatric surgery(body mass index ≥35 kg/m² or metabolic disease with body mass index 27.5-34.9 kg/m²), with planned Roux-en-Y gastric bypass or sleeve gastrectomy; 4. provision of written informed consent and willingness to complete follow-up. Exclusion Criteria: 1. gastrointestinal motility disorders; 2. severe cardiovascular, pulmonary, hepatic, or renal dysfunction; 3. HbA1c ≥8.0%; 4. fasting plasma glucose \>10.0 mmol/L at the preoperative assessment; 5. malnutrition; 6. known allergy to carbohydrate preparations; 7. pregnancy or lactation; 8. previous bariatric or gastrointestinal surgery; 9. chronic use of medications known to substantially affect gastrointestinal motility.
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What it tests

  • Preoperative oral carbohydrate loading
  • The placebo
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Where

1 site
The First Affiliated Hospital of Chongqing Medical University(No. 1 Youyi Road, Yuzhong District, Chongqing 400016, China)
Chongqing, China
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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