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โ† Trials
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Cardio-Oncology Rehabilitation in Breast Cancer Patients Undergoing Chemotherapy

RecruitingNAAges 18 Years - 65 YearsFemaleHospital de Clinicas de Porto Alegre
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In plain words

What the trial is, and whether it could suit you

Breast cancer is the most prevalent malignancy among women in Brazil, and Porto Alegre (Rio Grande do Sul) has one of the highest incidence rates in women under 50, with 165.5 cases per 100,000 women aged 40-49. Advances in cancer biology, treatment, and supportive care have improved outcomes, leading to increased survivorship. Regular physical exercise has been shown to be an effective strategy in both the prevention and management of breast cancer, and during chemotherapy, physical activity may reduce fatigue, improve quality of life, and increase cardiorespiratory fitness. This randomized clinical trial will enroll women diagnosed with breast cancer indicated for neoadjuvant or adjuvant chemotherapy. The study aims to characterize the clinical profile of these patients with respect to cardiovascular and functional effects of chemotherapy, and to evaluate an integrated cardio-oncology

Sign in to get the eligibility rules as simple questions to take to your doctor.

๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: 1. Diagnosis of breast cancer 2. Indicated for chemotherapy treatment 3. Cardiovascularly stable 4. Cleared for physical exercise 5. Willing to participate in the study 6. Physically able to perform the assessments and training sessions Exclusion Criteria: 1. Any decompensated disease that would compromise the ability to perform the training sessions 2. Prior diagnosis of ischemic heart disease 3. Prior diagnosis of valvular heart disease 4. Prior diagnosis of cardiac arrhythmias 5. Myocarditis within the past 6 months 6. History of heart failure 7. LVEF \<55% prior to initiation of chemotherapy 8. Musculoskeletal disorders that limit the ability to perform the exercises 9. Diagnosis of peripheral arterial occlusive disease within the past 6 months 10. Ankle-brachial index \<0.4 11. Cognitive impairment that would compromise understanding of study procedures or participation
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What it tests

  • Cardio-Oncology Exercise Rehabilitation Program
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Where

1 site
Hospital de Clinicas de Porto Alegre
Porto Alegre, Brazil
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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