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Comparison of Autologous Tooth and Bovine Xenograft in Periodontal Healing After Mandibular Third Molar Extraction

RecruitingNAAges 18 Years - anyAllUniversidad Complutense de Madrid
NCT07824518 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This study investigates the healing of periodontal defects on the distal surface of the second lower molars after the surgical extraction of impacted third molars. Specifically, it compares the effectiveness of autologous tooth graft particles (derived from the extracted third molar) with bovine xenograft particles, using blood clot healing as a control.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Adults (≥18 years old) of any sex, able to understand and follow study instructions. * Patients requiring bilateral surgical extraction of impacted lower third molars in horizontal or mesioangular position. * Presence of both lower second molars. * Classified as ASA I or ASA II (according to the American Society of Anesthesiologists). * Willingness to participate voluntarily and sign informed consent. Exclusion Criteria: * Age under 18 years. * ASA physical status III, IV, V, or VI. * Pregnant or breastfeeding women. * Immunosuppressed patients. * Current treatment with NSAIDs, anticoagulants, or acetylsalicylic acid. * Previous or current treatment with bisphosphonates. * Presence of oral dysplasia or precancerous lesions.
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What it tests

  • Autologous Tooth Graft
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Where

1 site
Postgrado de especialización en cirugía bucal e implantología, Facultad de Odontología, Universidad Complutense de Madrid
Madrid, Spain
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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