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Sutureless Hemorrhoidectomy Versus Conventional Ligation in Advanced Hemorrhoids

RecruitingNAAges 18 Years - anyAllSohag University
NCT07824999 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Hemorrhoidal disease is a frequent benign anorectal ailment in surgical practice. Conventional excisional hemorrhoidectomy using the Milligan-Morgan technique remains effective but is significantly limited by severe postoperative pain and related complications. Sutureless hemorrhoidectomy utilizing energy-based vessel sealing devices (such as LigaSure or Harmonic Scalpel) aims to minimize tissue trauma, blood loss, and postoperative discomfort. This prospective comparative randomized clinical trial aims to evaluate and compare the perioperative and postoperative outcomes of sutureless hemorrhoidectomy versus conventional ligation hemorrhoidectomy in adult patients with advanced (grades III and IV) hemorrhoidal disease.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Adult patients aged 18 years or older. * Patients with symptomatic grade III or grade IV hemorrhoidal disease. * Combined internal and external hemorrhoidal disease requiring excisional hemorrhoidectomy. * Recurrent bleeding, prolapse, pain, mucous discharge, or hygiene difficulty despite conservative or office-based treatment. Exclusion Criteria: * Patients younger than 18 years. * Grade I or grade II hemorrhoids suitable for conservative or office-based therapy. * Acute thrombosed external hemorrhoids requiring emergency management. * Associated anal fissure, fistula-in-ano, perianal abscess, or inflammatory bowel disease. * Suspected or confirmed colorectal malignancy\[cite: 1\]. * History of previous anorectal surgery\[cite: 1\]. * Bleeding diathesis, uncontrolled anticoagulant therapy, or severe coagulopathy\[cite: 1\].
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What it tests

  • Energy-based sutureless hemorrhoidectomy
  • Conventional Milligan-Morgan hemorrhoidectomy
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Where

1 site
Sohag University Hospital, Department of General Surgery
Sohag, Egypt
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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