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Nerve Block for Severe Abdominal Pain in the Emergency Department

RecruitingEARLY Phase 1Ages 18 Years - anyAllUniversity of California, Irvine
NCT07826936 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Currently, the standard treatment of nonsurgical abdominal pain in the Emergency Department (ED) includes narcotic pain medication. This can be addictive and contributes to the current opioid epidemic. Recent studies have shown that the Erector Spinae Plane Block (ESPB) is an alternative approach to achieving abdominal analgesia without the use of any systemic pain medications. It is a regional nerve block that can be used by emergency medicine physicians by injecting anesthetic into the erector spinae plane under ultrasound guidance, which effectively anesthetizes the abdomen. This procedure is within the scope of practice of Emergency Medicine residents, fellows, and attendings who have received training in Point-of-Care Ultrasound (POCUS) and who have also received specialized training on how to perform the ESPB under ultrasound guidance. Adult patients will be screened for intractabl

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📋 Eligibility rules (as published)
Inclusion Criteria: * Over 18 years of age * Abdominal pain that is intractable, defined as pain persisting despite administration of more than one dose of narcotic medication * Nonsurgical abdominal pain, determined by either a benign abdominal exam not warranting a computed tomography (CT) scan, or a CT scan showing no identifiable surgical process * Patient may present from the Emergency Department (ED) or may be an admitted inpatient Exclusion Criteria: * Under 18 years of age * Pregnant, confirmed by a positive pregnancy test sent on all female patients of childbearing age presenting with abdominal pain * Psychiatric patients * Unable to verbalize a pain score, or impaired decision-making capacity (e.g., obtunded, intoxicated, lethargic, critically ill, intubated, or cognitively impaired) * Any contraindication to nerve blocks, such as infection overlying the injection site, a bleeding disorder, or an allergy to anesthetic * Surgical abdomen requiring serial abdominal exams
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What it tests

  • Bupivacaine (erector spinae plane block)
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Where

1 site
UC Irvine, Department of Emergency Medicine
Orange, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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