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Hospital-Based Prospective Cohort of Malnutrition Under 6-Month Study (HOSPIC-6-Study)

Recruitingn/aAges 1 Day - 6 MonthsAllUniversitas Indonesia
NCT07831343 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This study is a hospital-based, prospective, multicentre cohort study (the HOSPIC-6 Study) that will follow infants under 6 months of age who are admitted to pediatric or perinatology wards with acute malnutrition, diagnosed according to the 2023 WHO criteria. The study will take place at Cipto Mangunkusumo Hospital (RSCM) in Jakarta, Indonesia, together with other hospitals all over Indonesia joining the HOSPIC-6 network, over a period of about one year. The purpose of this study is to: 1. Describe how common acute malnutrition is among infants under 6 months admitted to these hospitals 2. Observe what happens to these infants during nutrition treatment: whether they recover, whether their growth improves, or whether they experience complications or death. 3. Look at the factors associated with succesful nutrition therapy outcomes. After enrolment, each infant's weight, length, head

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📋 Eligibility rules (as published)
Inclusion criteria: * Infants under 6 months of age admitted to inpatient care who meet the WHO 2023 criteria for acute malnutrition. * For infants aged 0-1 month, criteria include a documented weekly weight gain of less than 200 grams, or failure to return to birth weight by 2 weeks of chronological age. * For infants aged 1 month to under 6 months, at least one of the following is required: * Weight-for-age less than -2 SD * Weight-for-length less than -2 SD, or * Mid-upper arm circumference under 110 mm (for infants older than 6 weeks), with or without nutritional oedema, and currently receiving treatment for acute malnutrition. * Parents or legal guardians must provide written informed consent. Exclusion criteria: * Infants with inborn error of metabolism * Infant with syndromic condition (e.g., Down syndrome, Silver-Russell syndrome, Turner syndrome, Klinefelter syndrome, or other diagnosed syndromic conditions), * Infant with anatomical abnormality affecting body weight, such as hydrocephalus. Drop Outs Criteria: Participants will be considered "drop-outs" if they are discharged against medical advice or transferred to a non-participating hospital.
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What it tests

  • Not applicable- observational study
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Where

10 sites
RSUP Dr. Kariadi Semarang
Semarang, Indonesia
RSUP Dr. Sardjito
Yogyakarta, Indonesia
Cipto Mangunkusumo Hospital
Jakarta Pusat, Indonesia
RSIA Bunda Jakarta
Jakarta Pusat, Indonesia
RSAB Harapan Kita
Jakarta Pusat, Indonesia
RSUD H. Abdul Manap Kota Jambi
Jambi City, Indonesia
RSUP Prof. Dr. R. D. Kandou
Manado, Indonesia
RSUP Dr. Hasan Sadikin
Bandung, Indonesia

…and 2 more on ClinicalTrials.gov.

🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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