Chinese Multicenter Cohort Study of Intracerebral Hemorrhage

Inclusion Criteria - Intracerebral Hemorrhage Cohort: * Age 18 years or older. * Intracerebral hemorrhage confirmed by head computed tomography and/or magnetic resonance imaging. * Hemorrhage located in a deep cerebral region, cerebral lobe, cerebellum, or brainstem. * Presentation to a participating hospital within 30 days after symptom onset. * Written informed consent and broad consent provided in accordance with the ethics-approved process. Exclusion Criteria - Intracerebral Hemorrhage Cohort: * Traumatic intracerebral hemorrhage. * Secondary intracerebral hemorrhage attributed to an arteriovenous malformation, ruptured aneurysm, moyamoya disease, cavernous malformation, hematologic disorder, hemorrhagic tumor, vasculitis, cerebral venous thrombosis, hemorrhagic transformation of cerebral infarction, or other prespecified secondary cause. * Mixed intracerebral hemorrhage involving multiple deep and lobar locations at onset. * Severe psychiatric disease that precludes study procedures or follow-up. * End-stage hepatic or renal failure. * Autoimmune disease judged by the investigator to materially affect study objectives. * Active malignant tumor. * Pregnancy. * Any other condition that the investigator judges makes participation inappropriate. Inclusion Criteria - Healthy Control Cohort: * Age 18 years or older. * Able to provide written informed consent. * No known history of intracerebral hemorrhage. Exclusion Criteria - Healthy Control Cohort: * Malignant tumor. * Neurologic disease, particularly any prior intracerebral hemorrhage. * Any other condition that the investigator judges makes participation inappropriate.