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Anti-Inflammatory Diet and Physical Activity for Reproductive Health in Adolescent Girls

RecruitingNAAges 14 Years - 19 YearsFemalePoznan University of Physical Education
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In plain words

What the trial is, and whether it could suit you

This study will evaluate whether a 16-week anti-inflammatory dietary intervention, delivered alone or together with a physical activity programme, can improve diet quality and support reproductive health in girls aged 14-19 years. Approximately 100 participants will be recruited from two secondary schools in Poland. Participants at both schools will receive education and practical guidance on an anti-inflammatory diet based on Mediterranean dietary principles. Participants at one school will additionally take part in a supervised physical activity programme conducted twice weekly. The primary outcome will be the change in diet quality assessed using the KIDMED index. Additional assessments will examine menstrual health, premenstrual symptoms, menstrual pain, physical activity, body composition, anthropometric measures, selected salivary biomarkers, and the oral microbiome. Assessments w

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📋 Eligibility rules (as published)
Inclusion Criteria: Female adolescents aged 14 to 19 years * Attendance at one of the participating secondary schools * Provision of written informed consent by the participant and, for participants below the age of legal consent, by a parent or legal guardian * Willingness to participate in the study assessments and the assigned 16-week intervention Exclusion Criteria: * Presence of systemic or hereditary diseases Thyroid dysfunction, diabetes mellitus, congenital adrenal hyperplasia, Cushing syndrome, hyperprolactinemia suggestive of a pituitary adenoma, or an androgen-secreting tumour. * Severe salivary gland dysfunction, including Sjögren syndrome * Chronic use of medications, hormonal therapy, antibiotic treatment, or regular use of dietary supplements with potential effects on hormonal, inflammatory, oxidative stress, or microbiome-related outcomes within the previous three months. * Regular alcohol consumption or tobacco smoking * Allergy to olive oil, nuts, legumes, spices, or herbs * Medical contraindications to physical exercise or participation in the training programme. Participants with acute oral infections, gingival bleeding, or other oral conditions affecting the reliability of oral microbiome assessments may remain eligible for the other study assessments but will not be included in the relevant oral microbiome analyses.
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What it tests

  • Anti-Inflammatory Dietary Intervention
  • Physical Activity and Training Programme
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Where

2 sites
Liceum Ogólnokształcące Św. Marii Magdaleny
Poznan, Poland
Liceum Ogólnokształące im. Powstanców Wielkopolskich
Środa Wielkopolska, Poland
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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