💬In plain words
What the trial is, and whether it could suit you
To analyze the environmental risk factors for type 1 diabetes in China.
Sign in to get the eligibility rules as simple questions to take to your doctor.
📋 Eligibility rules (as published)
Inclusion Criteria:
1. Individuals with type 1 diabetes (no age restriction):
* Clinically diagnosed with T1D by a specialist.
* Meeting any one of the following conditions:(1) Age of onset \< 15 years;(2) No overweight or obesity at onset;(3) History of ketoacidosis.
* Insulin-dependent since disease onset;
* Positive for at least one islet autoantibody (GADA, IA-2A, ZnT8A, IAA, ICA);
* Disease duration ≤ 3 years.
2. First-degree relatives:
* Parents, siblings, or children of an individual with T1D.
* Age ≤ 45 years.
Exclusion Criteria:
1. Individuals with type 1 diabetes
* Gestational diabetes.
* Confirmed monogenic diabetes.
* Secondary diabetes.
* Type 2 diabetes.
* Other specific types of diabetes.
2. First-degree relatives:
* Diagnosed with diabetes before screening;
* Previous or current use of glucose-lowering drugs.
Common exclusion criteria:
* Severe active disease or a condition likely to substantially affect life expectancy, including malignancy or severe cardiac, pulmonary, hepatic, or renal disease.
* A condition that may require immunosuppressive therapy during the study period.
* Current systemic immunosuppressive therapy.
* Current systemic glucocorticoid therapy.
* Participation in another drug or medical device trial during recruitment or the study period.
* History of major surgery or severe trauma.
HealthTeky