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Histological and Histomorphometric Assessment With Inflammatory Profile Analysis of Bone Tissue After Horizontal Ridge Augmentation Using Customized Porous Zirconia Shell

RecruitingNAAges 21 Years - anyAllMohammed Mahmoud Abed
NCT07841158 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The goal of this clinical study is to learn whether a custom-made porous zirconia shell can support good-quality new bone when widening the lower back jaw before dental implant placement. The study includes adults whose jawbone in this area is too narrow for implants (Seibert Class I defects). The main question it aims to answer is: What is the quality of the new bone formed under a porous zirconia shell, and how much inflammation does the tissue show? Participants will: * Receive gum treatment and a CBCT scan before surgery * Have bone augmentation surgery, in which a digitally designed porous zirconia shell is fixed over a mixture of their own bone and xenograft * Return after 2 weeks for suture removal and a check of the wound * Return after 6 months for a CBCT scan, removal of the shell, collection of a small bone sample (biopsy), and dental implant placement

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📋 Eligibility rules (as published)
Inclusion Criteria: * Age more than 21 years old * Horizontal bone loss in the lower posterior area (Seibert Class I) * Enough inter-arch space for placement of implant-supported prosthesis * Motivated patient to have the treatment * Good oral hygiene Exclusion Criteria: * Patients with systemic conditions that could interfere with the healing process * Pregnant females * Smokers * Poor oral hygiene
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What it tests

  • Customized porous zirconia shell
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Where

1 site
October University for Modern Sciences and Arts (MSA), Faculty of Dentistry
Giza, Egypt
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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