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โ† Trials
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Evaluation of Blood-Based Biomarkers and Remote Cognitive Assessment for Dementia Triage (SANDBOX)

Recruitingn/aAges 50 Years - anyAllPrima Mente
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In plain words

What the trial is, and whether it could suit you

Dementia is a leading cause of death in the UK, and long waits for diagnosis can delay access to care and treatment. The SANDBOX study is a research study in NHS Memory Clinics investigating whether providing clinicians with additional test results could help them diagnose dementia earlier. Adults aged 50 or over who have been referred to a Memory Clinic by their GP may be invited to take part. Taking part is voluntary and will not affect a participant's care. Participation adds to their NHS care and does not replace or delay it. Participants complete three assessments: a blood test that measures two proteins which can indicate whether Alzheimer's-related changes may be happening in the brain (not currently available on the NHS); a genetic test for the APOE gene, which influences Alzheimer's risk; and a cognitive assessment of memory and thinking that includes a recorded speech task an

Sign in to get the eligibility rules as simple questions to take to your doctor.

๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * The participant is willing and able to provide informed consent for participation in the study, or if unable to consent, a consultee (nearest of kin or holder of Power of Attorney) is available to make a declaration. * Eligibility for recruitment in Scotland is restricted to participants who are able to provide informed consent themselves; participants requiring consultee consent will not be recruited in Scotland. * Male or female, aged 50 years or older. * The participant is currently on a waiting list for a participating Memory Clinic. * The participant lives within traveling distance to a study site. * The participant agrees to complete all study procedures, including genetic testing. Exclusion Criteria: * The participant may not enter the study if any of the following criteria apply: * The participant has known or anticipated challenges with venous blood sampling. * The participant is not fluent in English. * The participant has a historical diagnosis of dementia.
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What it tests

  • Not listed
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Where

12 sites
Imperial College Healthcare NHS Trust
London, United Kingdom
Central and North West London NHS Foundation Trust
London, United Kingdom
West London NHS Trust
London, United Kingdom
Surrey and Borders Partnership NHS Foundation Trust
London, United Kingdom
Aneurin Bevan University Health Board Clinical Research Centre
Newport, United Kingdom
Bradford District Care Foundation Trust
Bradford, United Kingdom
Cwm Taf Morgannwg University Health Board
Bridgend, United Kingdom
Hywel Dda University Health Board
Llanelli, United Kingdom

โ€ฆand 4 more on ClinicalTrials.gov.

๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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