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โ† Trials
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Clinical Evaluation of a Toothpaste for Dental Plaque Reduction and Prevention of Gum Problems

RecruitingPhase 3Ages 18 Years - 70 YearsAllColgate Palmolive
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In plain words

What the trial is, and whether it could suit you

Qualified subjects will be enrolled and randomized to either one of the three study groups described above based on their initial modified gingivitis and plaque scores. Subjects will be instructed to use the products according to the instructions provided. Subjects will return to the dental office for evaluation after three months and six months of product use. All subjects will be followed for adverse events throughout the study.

Sign in to get the eligibility rules as simple questions to take to your doctor.

๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * Subjects, ages 18-70, inclusive. * Availability for the six-month duration of the study. * Good general health. * Initial gingivitis index of at least 1.5 as determined by the use of the Modified Gingivitis Index. * Initial plaque index of at least 1.5 as determined by the use of the Modified Quigley-Hein Plaque Index. * Signed Informed Consent Form Exclusion Criteria: * Orthodontic bands. * Tumor(s) of the soft or hard tissues of the oral cavity. * Advanced periodontal disease (purulent exudate, tooth mobility), and/or * Extensive loss of periodontal attachment or alveolar bone. * Five or more carious lesions requiring immediate restorative treatment * Use of antibiotics any time during the one month prior to entry into the study. * Participation in any other clinical study or test panel within the one month prior to entry into the study. * Received a dental prophylaxis in the two weeks prior to your initial examination. * History of allergies to oral care/personal care consumer products or their ingredients. * Having taken any prescription medicines that might interfere with the study outcome. * If you with an existing medical condition which prohibits you from not eating or drinking for periods of up to 4 hours. * Self-reported pregnant or breast feeding an infant. * History of drug abuse
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What it tests

  • 0.45% SnF HW with NaF (1450 F)
  • 67% Bicarbonate with NaF (1400 F)
  • Colgate Cavity Protection Toothpaste
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Where

1 site
Clinica Odontoiatrica Montesani
Roma, Italy
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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