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3D MRE-Based Evaluation of Vestibular Schwannoma Mechanical Properties and Histological Features

Recruitingn/aAges 18 Years - 75 YearsAllShengjing Hospital
NCT07844460 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This prospective single-center study aims to evaluate the feasibility and clinical utility of three-dimensional magnetic resonance elastography (3D MRE) in assessing tumor stiffness and adhesion in patients with vestibular schwannoma undergoing surgical resection. By correlating preoperative MRE-derived stiffness and adhesion maps with intraoperative findings and histopathological features, the study seeks to determine whether MRE can serve as a noninvasive imaging biomarker for risk stratification and prediction of tumor behavior, and to evaluate the relationship between MRE characterization of tumor mechanical features and patients' clinical prognosis.

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📋 Eligibility rules (as published)
Inclusion Criteria: -All patients undergoing vestibular schwannoma resection surgery are eligible for inclusion in the study cohort. Exclusion Criteria: * Patients with metallic implants or foreign bodies in their bodies (pacemakers, artificial metallic heart valves, metal joints, metal implants, and those who can not remove dentures, insulin pumps, or contraceptive rings) * Pregnant women in the first trimester (within three months) * Patients with severe claustrophobia or anxiety * Patients with severe fever * Patients who can not tolerate MRE * Patients with vascular malformations and aneurysms. * Patients who do not sign an informed consent
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What it tests

  • Not listed
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Where

1 site
Shengjing hospital
Shenyang, China
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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