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โ† Trials
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China Aortic Infection and Graft Infection Study: An Ambispective Cohort

Recruitingn/aAges 18 Years - anyAllShanghai Zhongshan Hospital
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In plain words

What the trial is, and whether it could suit you

Vascular infections are uncommon but severe infections involving the arterial wall, vascular grafts, or endografts, and their diagnosis and management remain challenging. The CAIGIS Cohort is an ambispective observational cohort established at Zhongshan Hospital, Fudan University, to create an integrated clinical research platform and biobank for patients with suspected or confirmed vascular infections. The primary research focus is the diagnosis and characterization of causative pathogens. Conventional microbiological methods and emerging molecular diagnostic technologies will be systematically evaluated, with particular emphasis on blood-based pathogen detection as a form of liquid biopsy and its diagnostic value compared with local tissue or operative specimens. Serial blood samples and tissue specimens, when available, will also be used to investigate biomarkers associated with trea

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๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: 1. Adults aged 18 years or older. 2. Patients with suspected or confirmed vascular infection involving the native arterial wall, vascular graft, or endograft, including but not limited to infectious aortitis, infected arterial aneurysm, vascular graft or endograft infection, and fistula-associated vascular infection. 3. Patients evaluated or treated at Zhongshan Hospital, Fudan University, with sufficient clinical information to allow diagnostic adjudication and outcome assessment. 4. For the prospective cohort, willingness to participate and provide informed consent when required. 5. For the retrospective cohort, availability of relevant clinical records meeting the requirements approved by the institutional ethics committee. Exclusion Criteria: 1. Isolated superficial surgical-site infection without evidence of involvement of the arterial wall, vascular graft, or endograft. 2. Insufficient clinical data to permit diagnostic adjudication or longitudinal outcome assessment. 3. Refusal to participate in the prospective component when informed consent is required.
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What it tests

  • Not listed
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Where

1 site
Zhongshan Hospital, Fudan University
Shanghai, China
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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