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Impact of Entropy Monitoring on Anesthetic Consumption and Recovery After Laparoscopic Cholecystectomy

RecruitingNAAges 18 Years - 60 YearsAllKRL Hospital, Islamabad
NCT07847788 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The goal of this clinical trial is to learn if brainwave-guided anesthesia (entropy monitoring) can reduce anesthetic drug consumption and speed up recovery time in adult patients undergoing elective laparoscopic cholecystectomy surgery under general anesthesia. The main questions it aims to answer are: * Does entropy monitoring significantly decrease the mean consumption rate of sevoflurane gas (in mL/hr) compared to traditional clinical monitoring during surgery? * Does entropy monitoring significantly reduce the mean recovery time (in minutes to open eyes on verbal command) after discontinuing anesthesia? Researchers will compare patients whose anesthesia depth is guided by real-time entropy monitoring (brainwave and facial muscle sensors) to patients whose anesthesia is guided by standard clinical signs (heart rate and blood pressure) to see if using entropy sensors reduces total a

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📋 Eligibility rules (as published)
Inclusion Criteria: * ASA I or II * Elective laparoscopic cholecystectomy under GA Exclusion Criteria: * Emergency cholecystectomy * Co Morbid (Hypertension, Diabetes Mellitus, Ischemic Heart Disease, Chronic Kidney Disease, Asthma, Stroke) * Known allergy or contraindication to sevoflurane or study drugs * Addictions such as chronic use of sedatives, hypnotics or alcohol abuse on medical records * BMI of 30 or greater (Obese patients tend to have delated recovery from general anesthesia) * Pregnancy
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What it tests

  • Entropy Monitoring-Guided Anesthesia Titration
  • Standard Clinical Parameter-Guided Anesthesia Titration
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Where

1 site
KRL Hospital Islamabad
Islamabad, Pakistan
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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