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← Trials
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Effect of Melatonin on Pulmonary Hypertension in Full Term Neonates

RecruitingNAAges any - anyAllAin Shams University
NCT07850934 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The aim of the study 1. To evaluate safety and efficacy of melatonin as an adjuvant therapy to inhaled nitric oxide generated by NO generator in the treatment of pulmonary hypertension in full term neonates. 2. To assess the effect of inhaled nitric oxide and melatonin on cerebral perfusion.

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📋 Eligibility rules (as published)
Inclusion criteria : * Term neonates with gestational age ≥ 37 weeks. * Mean Pulmonary artery pressure greater than 25mmHg with clinical manifestations as tachypnea, tachycardia, hypoxemia and hypotension Exclusion criteria : * Congenital methemoglobinemia. * Major congenital cardiac anomalies especially duct dependent systemic circulation. * Bleeding tendency. * Patients on other pulmonary vasodilators
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What it tests

  • Melatonin
  • nitric oxide generator
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Where

1 site
Ain Shams University
Cairo, Egypt
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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