miRNA to Guide Appropriate Intervention of Small Testis Masses

Inclusion Criteria: * • Small testicular mass/masses ≤ 2cm * Patients with serum tumour marker elevation are eligible only if they are considered for surgical treatment, or if markers are felt to be falsely elevated by the physician team * If the patient previously had chemotherapy, the mass must first have appeared only after the treatment completed * The patient is at least 18 years of age * Ability to understand and comply with the requirements of the study * Ability to understand and willingness to sign a written informed consent Exclusion Criteria: * • Patients with testicular tumours \> 2 cm * Metastatic disease * Patients in reduced general condition, with uncontrolled intercurrent illnesses, or with life-threatening disease * Patients with psychiatric illnesses that would limit compliance with study requirements * Clinical decision is made by the multidisciplinary team that patient is not suitable for surveillance