Natural History Study of Advanced RCD

Inclusion Criteria: 1. Males and females 18 years of age or older, with history of formed vision 2. Clinical diagnosis of advanced retinal degeneration due to RCD 3. BCVA no better than (≥) 1.0 LogMAR (≤35 Early-Treatment Diabetic Retinopathy Study \[ETDRS\] letters, or 20/200 Snellen equivalent) in at least one eye 4. Documented preservation of foveal Outer Nuclear Layer (ONL) in at least one eye Exclusion Criteria: 1. Individuals who are receiving or have received an investigational medicinal product (IMP) in another clinical trial are excluded from the prospective part . However, they can participate in the retrospective part of the study. 2. Individuals with a medical condition (systemic or ophthalmic), psychiatric condition (including substance abuse disorder), physical examination or laboratory findings that may in the opinion of the Investigator preclude adherence to the scheduled study visits, safe participation in the study, or affect study results are excluded from participating in in-person study visits. However, they can participate in the collection of data reported during both retrospective and prospective SoC routine eye examinations.