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Quadriceps Muscle Activity and Gait Kinematics in Patients With Post-Stroke Stiff-Knee Gait Compared With Healthy Controls

Recruitingn/aAges 18 Years - anyAllFrédéric Chantraine
NCT07857967 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Stiff-knee gait (SKG) is a frequent gait abnormality in people with post-stroke hemiparesis and is characterized by insufficient knee flexion during the swing phase of walking. One potential mechanism is inappropriate activation of one or more heads of the quadriceps during pre-swing and early swing. This observational study will compare quadriceps electromyographic activity and gait kinematics between adults with chronic post-stroke hemiparesis with SKG and healthy adult controls. The study will include 30 participants with post-stroke SKG and 24 healthy controls. Quantitative gait analysis will be performed using three-dimensional motion analysis together with electromyography (EMG). Ultrasound-guided fine-wire electrodes will record the activity of all four heads of the quadriceps: rectus femoris, vastus intermedius, vastus medialis, and vastus lateralis. Healthy controls will be a

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📋 Eligibility rules (as published)
Inclusion Criteria (Post-Stroke SKG Group): * Clinical diagnosis of cerebral stroke with hemiparesis. * Age greater than 18 years. * Right- or left-sided hemiparesis following stroke. * Stroke occurred at least 6 months before assessment. * Able to walk independently without a technical walking aid. * Reduced knee flexion during the swing phase of gait (stiff-knee gait) identified by visual observation by an experienced clinician. Exclusion Criteria (Post-Stroke SKG Group): * Other disease or history of disease likely to influence gait, including peripheral neurological, cerebellar, vestibular, rheumatological, orthopedic, or metabolic disorders. * Visual or hearing impairment. * Medication likely to affect gait. * Botulinum toxin injection into the lower-limb muscles within the preceding 6 months * Use of illicit substances within 24 hours before the gait assessment. Inclusion Criteria (Healthy-Control Group): * Age greater than 18 years. * No pathology likely to alter gait. * No abnormality of knee kinematics identified during visual observation by an experienced clinician.
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What it tests

  • Not listed
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Where

1 site
Centre National de Rééducation Fonctionnelle et de Réadaptation
Luxembourg, Luxembourg
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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