🌐 EnglishEN

AI Cure is a research tool showing open data. Not medical advice. Discuss with your doctor. Terms

← Trials
🧪

Effects of Wheat Flour Milling Method on Glycemic Response and Gastrointestinal Symptoms

RecruitingNAAges 20 Years - 40 YearsAllUniversity of Bergen
NCT07858110 on ClinicalTrials.gov ↗
💬

In plain words

What the trial is, and whether it could suit you

The goal of this clinical trial is to learn if the way wheat flour is ground - by stone milling (an older method) or roller milling (used for most flour today) - changes blood sugar levels after eating bread, in healthy adults aged 20 to 40 who eat bread regularly. The main questions it aims to answer are: Does bread made from stone-milled flour cause a smaller rise in blood sugar after breakfast than bread made from roller-milled flour? Does the milling method change stomach symptoms such as bloating? Researchers will compare bread made from stone-milled wheat flour to bread made from roller-milled wheat flour, made from the same wheat and prepared the same way, to see if milling method changes blood sugar and stomach symptoms. Participants will: Eat the study bread at breakfast and lunch for 3 days, then switch to the other bread for 3 days, in a random order Eat a standard bread f

Sign in to get the eligibility rules as simple questions to take to your doctor.

Sign in
📋 Eligibility rules (as published)
Inclusion Criteria: * BMI 18.5-25 kg/m2 * Healthy, defined by reference to the exclusion criteria below * Habitual consumption of bread on most days, at more than one meal per day * Willing and able to consume the study breads, to follow the standardized meal pattern for 14 days, and to wear a CGM sensor continuously for 14 days Exclusion Criteria: * Smoking/tobacco use * Any disease or condition or use of drugs or other compounds or treatments that could have a clinically significant impact on energy metabolism and/or gastrointestinal health (Roma IV to rule out IBS) * Diagnosed diabetes mellitus of any type (no screening measure of glycemic status will be obtained because sample collection is minimized within the project resources) * Diagnosed celiac disease, or self-reported gluten or wheat sensitivity leading to habitual avoidance of wheat products * Pregnancy or lactation * Systemic antibiotic use within 4 weeks before the calibration visit * Night-shift or rotating-shift work during the study period * Skin condition at the sensor site precluding CGM wear * No allergies to wheat/grains
💊

What it tests

  • Stone-milled wheat flour bread
  • Roller-milled wheat flour bread (sourdough)
📍

Where

1 site
Research Unit for Health Surveys, University of Bergen
Bergen, Norway
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
🛡️

AI Cure shows public evidence (Open Targets, ClinicalTrials.gov, PubMed, openFDA, DepMap, AlphaFold) with its source, and AI summaries that cite it — not medical advice and not a cure. Treatment decisions belong with your doctor. Research ideas are shared only with approved researchers and labs, who can test them. In an emergency call your local emergency number (112 in India and Europe, 911 in the US). AI Cure Terms of Use · Privacy