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Supplementation of Cholecalciferol and Related Active Metabolites Through Bioenhancing Layer's Eggs

RecruitingNAAges 18 Years - 40 YearsAllCornell University
NCT07859280 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The purpose of this research is to evaluate if 1) consumption of vitamin D3- or 25(OH)D3-biofortified eggs will increase vitamin D and 25(OH)D status in young adults who consume these bioenhanced eggs, 2) to determine if the gut microbiome profile is associated with 25(OH)D or vitamin D status and 3) to evaluate possible changes in the gut microbiome following an 8-week supplementation period providing 5(OH)D- or vitamin D bioenhanced eggs.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Healthy adults * Non-smoking * Age between 18- 40 years * Females: premenopausal and not pregnant or lactating * Body mass index (BMI) between 18.5-27.0 kg/m2. * No planned trip(s) to lower latitudes during the 8-week study Exclusion Criteria: * BMI \<18.5 or \> 27.0 kg/m2, * Age \<18 y or \> 40y, * Smoking * Pregnancy, lactating * Have gastrointestinal disorders/malabsorption diseases/dietary restrictions/use of medications known to impact vitamin D and 25(OH)D absorption * Been prescribed antibiotics within 3 months before enrolling * History or current diagnosis of any of the following conditions: intestinal problems (cystic fibrosis, Crohn's Disease, IBD, etc.), blood disorders (sickle cell, thalassemia, etc.), stomach problems (ulcers or other problems requiring antacids), joint diseases requiring anti-inflammatory medication, or asthma. * Planned trip(s) to lower latitudes during the 8-week study
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What it tests

  • Vitamin D3 bioenhanced eggs
  • 25(OH)D3 bioenhanced eggs
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Where

1 site
Human Metabolic Research Unit
Ithaca, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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