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Ultrasound-Guided Repeated Saline Injections to Prevent and Treat Tendon Adhesions After Hand Tendon Repair

RecruitingNAAges 18 Years - 60 YearsAllKai Wang
NCT07861568 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Scar tissue can form around a repaired tendon and restrict finger movement. This study will evaluate whether repeated ultrasound-guided normal saline injections, in addition to standard postoperative rehabilitation, can help prevent and treat tendon adhesion after surgical repair of zone II flexor tendon injuries. The study is a prospective, single-center, randomized controlled trial involving 80 adults aged 18 to 60 years with a zone II flexor tendon rupture in the index, middle, ring, or little finger. Participants will be assigned to one of two groups, with 40 participants in each group. Participants in both groups will receive the same standard postoperative rehabilitation treatment, including early active finger mobilization. In addition to this rehabilitation, the experimental group will receive ultrasound-guided percutaneous injections of 1 mL of normal saline at the tendon adhes

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📋 Eligibility rules (as published)
Inclusion Criteria: 1. Age 18 to 60 years. 2. Zone II flexor tendon rupture in the index, middle, ring, or little finger. 3. Scheduled to undergo tendon repair surgery. Exclusion Criteria: 1. Concomitant irreparable vascular and/or nerve injury. 2. History of diabetes mellitus. 3. History of treatment with nonsteroidal anti-inflammatory drugs. 4. History of cardiac insufficiency. 5. History of hematologic disease. 6. History of hepatic or renal dysfunction. 7. History of rheumatic or autoimmune disease. 8. History of chemotherapy or radiotherapy. 9. History of steroid treatment. 10. Pregnancy. 11. Concurrent participation in another clinical trial.
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What it tests

  • Ultrasound-Guided Repeated Normal Saline Injections
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Where

1 site
Shanghai sixth people's hospital
Shanghai, China
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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