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Role of Postpartum Furosemide in Recovery of Patients With Severe Preeclampsia

RecruitingNAAges 18 Years - 45 YearsFemaleLady Reading Hospital, Pakistan
NCT07861685 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This randomized controlled trial will compare oral furosemide with placebo for improving blood pressure control in women with severe preeclampsia after delivery. Participants will receive either 20 mg of furosemide or a placebo tablet once daily for 5 days, in addition to standard postpartum treatment for high blood pressure. Blood pressure, symptoms, adverse events, and the need for additional antihypertensive medication will be monitored for 7 days after delivery. The study will assess whether adding furosemide helps achieve better postpartum blood pressure control compared with placebo.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Women aged 18 to 45 years * Any parity * Gestational age \>28 weeks based on LMP * Severe preeclampsia as per the study operational definition Exclusion Criteria: History of underlying cardiac disease during pregnancy or postpartum * Pre-existing renal dysfunction or serum creatinine \>1.2 mg/dL on medical record * Significant hypokalemia (K \<3 mEq/L) before enrollment * Known rheumatologic disease or advanced diabetes * History of allergy to furosemide or prior use of diuretics before randomization * History of thyroid disorders or other medical illnesses that may interfere with blood pressure management
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What it tests

  • Furosemide and Potassium
  • Placebo
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Where

1 site
Lady Reading Hospital
Peshawar, Pakistan
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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